RRBP1 抗体
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北京 101111
Quick Overview for RRBP1 抗体 (ABIN7882178)
抗原
See all RRBP1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- RRBP1 Antibody / Ribosome binding protein 1
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序列
- EKEKKLTSDL GRAATRLQEL LKTTQEQLAR EKDTVKKLQE QLEKAED
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纯化方法
- Antigen affinity purified
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免疫原
- Amino acids EKEKKLTSDLGRAATRLQELLKTTQEQLAREKDTVKKLQEQLEKAED from the human protein were used as the immunogen for the RRBP1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the RRBP1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the RRBP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- RRBP1 (Ribosome Binding Protein 1 (RRBP1))
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别名
- RRBP1
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背景
- Ribosome-binding protein 1, also referred to as p180, is a protein that in humans is encoded by the RRBP1 gene. It is mapped to 20p12.1. This gene encodes a ribosome-binding protein of the endoplasmic reticulum (ER) membrane. Studies suggest that this gene plays a role in ER proliferation, secretory pathways and secretory cell differentiation, and mediation of ER-microtubule interactions. Alternative splicing has been observed and protein isoforms are characterized by regions of N-terminal decapeptide and C-terminal heptad repeats. Splicing of the tandem repeats results in variations in ribosome-binding affinity and secretory function. The full-length nature of variants which differ in repeat length has not been determined. Pseudogenes of this gene have been identified on chromosomes 3 and 7, and RRBP1 has been excluded as a candidate gene in the cause of Alagille syndrome, the result of a mutation in a nearby gene on chromosome 20p12.
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UniProt
- Q9P2E9
抗原
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