MASP2 抗体
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Quick Overview for MASP2 抗体 (ABIN7881549)
抗原
See all MASP2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- MASP2 Antibody
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序列
- EAGQYGVYTK VINYIPWIEN IISDF
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纯化方法
- Affinity purified
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免疫原
- Amino acids EAGQYGVYTKVINYIPWIENIISDF from the human protein were used as the immunogen for the MASP2 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the MASP2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the MASP2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- MASP2 (Mannan-Binding Lectin serine Peptidase 2 (MASP2))
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别名
- MASP2
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背景
- Mannan-binding lectin serine protease 2 is a protein that in humans is encoded by the MASP2 gene. This gene is mapped to 1p36.22. This gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is proteolytically processed to generate A and B chains that heterodimerize to form the mature protease. This protease cleaves complement components C2 and C4 in order to generate C3 convertase in the lectin pathway of the complement system. The encoded protease also plays a role in the coagulation cascade through cleavage of prothrombin to form thrombin. Myocardial infarction and acute stroke patients exhibit reduced serum concentrations of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
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UniProt
- O00187
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途径
- Complement System
抗原
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