Keratin 7/17 抗体
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北京 101111
Quick Overview for Keratin 7/17 抗体 (ABIN7881418)
抗原
See all Keratin 7/17 (KRT7/17) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- Cytokeratin 7/17 Antibody (azide and preservative free)
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纯化方法
- Protein G affinity chromatography
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免疫原
- A cytoskeletal preparation from human HeLa cells was used as the immunogen for this Cytokeratin 7/17 antibody.
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亚型
- IgG1, kappa
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anti-Keratin 7/17 (KRT7/17) antibody
KRT7/17 适用: 人, Cow, Pig WB, ICC, IHC (p), IP 宿主: 小鼠 Monoclonal C-46 unconjugated
anti-Keratin 7/17 (KRT7/17) antibodyKRT7/17 适用: 人, Cow IHC, WB, IF, FACS 宿主: 小鼠 Monoclonal C-46 unconjugated
anti-Keratin 7/17 (KRT7/17) antibodyKRT7/17 适用: 人, Cow, Pig IHC, WB, IP, IF/ICC 宿主: 小鼠 Monoclonal unconjugated
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应用备注
- Optimal dilution of the Cytokeratin 7/17 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the Cytokeratin 7/17 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Keratin 7/17 (KRT7/17)
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别名
- Cytokeratin 7/17
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背景
- It recognizes intermediate filament proteins (IFP's) of 55 kDa and 46 kDa, which are identified as Cytokeratin 7 and Cytokeratin 17 respectively. On formalin-fixed, paraffin embedded sections, C-46 reacts with Keratin 7 only. Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation, which is directly applicable to the characterization of malignant tumors. Cytokeratin 7 is a basic cytokeratin, which is found in most glandular and transitional epithelia but not in the stratified squamous epithelia. Cytokeratin 7 is expressed in the epithelial cells of ovary, lung, and breast but not of colon, prostate, or gastrointestinal tract. Cytokeratin 17 is expressed in epithelial cells of various origins, such as bronchial epithelial cells and skin appendages. Cytokeratin 17 antibody marks basal cell differentiation.
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UniProt
- P08729
抗原
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