JAK2 抗体
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北京 101111
Quick Overview for JAK2 抗体 (ABIN7881333)
抗原
See all JAK2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- JAK2 Antibody
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纯化方法
- Affinity purified
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免疫原
- A synthetic peptide specific to human JAK2 was used as the immunogen for the JAK2 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the JAK2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store the JAK2 antibody at -20oC.
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- JAK2 (Janus Kinase 2 (JAK2))
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别名
- JAK2
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背景
- Tyrosine-protein kinase JAK2 is a non-receptor tyrosine kinase involved in various processes such as cell growth, development, differentiation or histone modifications. Mediates essential signaling events in both innate and adaptive immunity. In the cytoplasm, plays a pivotal role in signal transduction via its association with type I receptors such as growth hormone (GHR), prolactin (PRLR), leptin (LEPR), erythropoietin (EPOR), thrombopoietin (THPO), or type II receptors including IFN-alpha, IFN-beta, IFN-gamma and multiple interleukins. [UniProt]
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UniProt
- O60674
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途径
- JAK/STAT Signaling, RTK signaling, Interferon-gamma Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling, Unfolded Protein Response
抗原
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