Recombinant HNRNPM 抗体
Our Local Distributor
北京 101111
Quick Overview for Recombinant HNRNPM 抗体 (ABIN7881033)
抗原
See all HNRNPM 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- HNRNPM Antibody / heterogeneous nuclear ribonucleoprotein M
-
纯化方法
- Affinity-chromatography
-
免疫原
- A synthesized peptide derived from human HNRNPM was used as the immunogen for the HNRNPM antibody.
-
亚型
- IgG
-
-
anti-Heterogeneous Nuclear Ribonucleoprotein M (HNRNPM) (AA 17-112) antibody
HNRNPM 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3F7 unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein M (HNRNPM) (AA 491-730) antibodyHNRNPM 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein M (HNRNPM) antibodyHNRNPM 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein M (HNRNPM) (AA 17-161) antibodyHNRNPM 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 5G6C11 unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein M (HNRNPM) (AA 17-112) antibodyHNRNPM 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2B6 unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein M (HNRNPM) (N-Term) antibodyHNRNPM 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein M (HNRNPM) (AA 17-113) antibodyHNRNPM 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3F7 unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein M (HNRNPM) (AA 491-730) antibodyHNRNPM 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein M (HNRNPM) antibodyKD Validated HNRNPM 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB4895 unconjugated Recombinant Antibody
anti-Heterogeneous Nuclear Ribonucleoprotein M (HNRNPM) (N-Term) antibodyHNRNPM 适用: 人, Cow, Pig, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal dilution of the HNRNPM antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store the HNRNPM antibody at -20oC.
-
-
- HNRNPM (Heterogeneous Nuclear Ribonucleoprotein M (HNRNPM))
-
别名
- HNRNPM
-
背景
-
HNRNPM antibody recognizes heterogeneous nuclear ribonucleoprotein M, an RNA-binding protein involved in pre-mRNA processing and splicing regulation. HNRNPM is part of the hnRNP family, which associates with nascent transcripts to influence alternative splicing, stability, transport, and translation. This protein is widely expressed and contributes to the regulation of diverse gene expression programs in normal development and stress adaptation.
Research using HNRNPM antibody has linked the protein to cancer progression and metastasis. By regulating alternative splicing of genes related to epithelial-to-mesenchymal transition (EMT), HNRNPM promotes tumor invasiveness and metastatic potential. Elevated expression of HNRNPM has been associated with poor prognosis in breast, colorectal, and liver cancers. Its role in RNA processing makes it a critical factor in understanding how splicing dysregulation contributes to oncogenesis.
Beyond cancer, HNRNPM has been implicated in immune function and neurobiology. Studies suggest roles in regulating splicing of immune-related transcripts and neuronal genes, connecting HNRNPM to autoimmune conditions and neurological disorders. Its widespread impact on RNA metabolism positions HNRNPM as an important regulator of cellular identity and function.
Antibodies against HNRNPM are validated for western blot, immunoprecipitation, immunohistochemistry, and immunofluorescence. Researchers use these reagents to analyze HNRNPM expression, splicing complex assembly, and transcript-specific binding. Clone-based antibodies offer the specificity needed to study this protein within large multi-protein RNA processing complexes.
NSJ Bioreagents offers this HNRNPM antibody for investigations into RNA splicing, cancer biology, and immune regulation. -
UniProt
- P52272
抗原
-
