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Growth Hormone Receptor 抗体

This 兔 单克隆 antibody specifically detects Growth Hormone Receptor in WB. It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN7880933
发货至: 中国
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Quick Overview for Growth Hormone Receptor 抗体 (ABIN7880933)

抗原

See all Growth Hormone Receptor (GHR) 抗体
Growth Hormone Receptor (GHR)

适用

  • 67
  • 44
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  • 17
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  • 2
  • 1
人, 小鼠

宿主

  • 65
  • 5
  • 1

克隆类型

  • 46
  • 25
单克隆

标记

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  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This Growth Hormone Receptor antibody is un-conjugated

应用范围

  • 51
  • 27
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  • 5
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  • 1
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Western Blotting (WB)

克隆位点

17G57
  • 原理

    GHR Antibody / Growth Hormone Receptor

    纯化方法

    Affinity purified

    免疫原

    A synthetic peptide specific to human Growth Hormone Receptor / GHR was used as the immunogen for the GHR antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the GHR antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store the GHR antibody at -20oC.
  • 抗原

    Growth Hormone Receptor (GHR)

    别名

    GHR

    背景

    The GHR gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. Multiple alternatively spliced transcript variants have been found for this gene. [RefSeq]

    UniProt

    P10912

    途径

    NF-kappaB Signaling, JAK/STAT Signaling, Response to Growth Hormone Stimulus
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