XPO1 抗体
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北京 101111
Quick Overview for XPO1 抗体 (ABIN7880757)
抗原
See all XPO1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- CRM1 Antibody / XPO1 / Exportin 1
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纯化方法
- Affinity purified
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免疫原
- A synthetic peptide specific to human CRM1 / XPO1 was used as the immunogen for the CRM1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the CRM1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store the CRM1 antibody at -20oC.
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- XPO1 (Exportin 1 (XPO1))
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别名
- CRM1
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背景
- Mediates the nuclear export of cellular proteins (cargos) bearing a leucine-rich nuclear export signal (NES) and of RNAs. In the nucleus, in association with RANBP3, binds cooperatively to the NES on its target protein and to the GTPase RAN in its active GTP-bound form (Ran-GTP). Docking of this complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins.
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UniProt
- O14980
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途径
- M Phase
抗原
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