CEA 抗体
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北京 101111
Quick Overview for CEA 抗体 (ABIN7880175)
抗原
See all CEA 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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原理
- CEA Antibody / Carcinoembryonic Antigen (azide and preservative free)
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纯化方法
- Protein A affinity
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免疫原
- Purified native human CEA protein was used as the immunogen for the CEA antibody.
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亚型
- IgG, kappa
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应用备注
- Optimal dilution of the CEA antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the CEA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- CEA (Carcinoembryonic Antigen Gene Family (CEA))
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别名
- CEA
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背景
- This antibody recognizes proteins of 80-200 kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70 % are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.
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UniProt
- P06731
抗原
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