Calnexin 抗体
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北京 101111
Quick Overview for Calnexin 抗体 (ABIN7880142)
抗原
See all Calnexin (CANX) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Calnexin Antibody
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纯化方法
- Protein G affinity chromatography
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免疫原
- A partial human recombinant protein was used as the immunogen for the Calnexin antibody.
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亚型
- IgG2b, kappa
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应用备注
- The stated application concentrations are suggested starting points. Titration of the Calnexin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the Calnexin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Calnexin (CANX)
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别名
- Calnexin
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背景
- Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse. [UniProt]
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UniProt
- P27824
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途径
- MAPK Pathway, Thyroid Hormone Synthesis
抗原
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