BNIP3L/NIX 抗体
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北京 101111
Quick Overview for BNIP3L/NIX 抗体 (ABIN7880065)
抗原
See all BNIP3L/NIX (BNIP3L) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Nix Antibody / BNIP3L
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纯化方法
- Affinity purified
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免疫原
- A synthetic peptide specific to human Nix / BNIP3L was used as the immunogen for the Nix antibody.
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亚型
- IgG
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anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L) (AA 43-130) antibody
BNIP3L 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3G2 unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L) (AA 1-187) antibodyBNIP3L 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L) (AA 52-81) antibodyBNIP3L 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB19646 unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L) antibodyBNIP3L 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L) (Internal Region) antibodyBNIP3L 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L) (AA 43-130) antibodyBNIP3L 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 2E11 unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L) (AA 1-187) antibodyBNIP3L 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1H10B3 unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L) (AA 59-89), (Middle Region) antibodyBNIP3L 适用: 人 WB, IF, IHC (p), FACS, EIA 宿主: 兔 Polyclonal unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L) (AA 51-150) antibodyBNIP3L 适用: 小鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L) (AA 1-187) antibodyBNIP3L 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the Nix antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store the Nix antibody at -20oC.
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- BNIP3L/NIX (BNIP3L) (BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L))
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别名
- Nix
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背景
- BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like' (BNIP3L), also called NIP3-like protein X (Nix) induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced by BNIP3. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates in mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. May function as a tumor suppressor. [UniProt]
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UniProt
- O60238
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途径
- Autophagy
抗原
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