alpha 2 Macroglobulin 抗体
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Quick Overview for alpha 2 Macroglobulin 抗体 (ABIN7879957)
抗原
See all alpha 2 Macroglobulin (A2M) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Alpha-2-macroglobulin Antibody / A2M
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纯化方法
- Affinity purified
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免疫原
- A synthetic peptide specific to human A2M / Alpha 2 Macroglobulin was used as the immunogen for the Alpha-2-macroglobulin antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Alpha-2-macroglobulin antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store the Alpha-2-macroglobulin antibody at -20oC.
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- alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))
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别名
- Alpha-2-macroglobulin
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背景
- Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum of proteases, including trypsin, thrombin and collagenase. It can also inhibit inflammatory cytokines, and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimer's disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [RefSeq]
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UniProt
- P01023
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途径
- Lipid Metabolism
抗原
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