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PAK2 抗体 (pSer20)

This anti-PAK2 antibody is a 兔 多克隆 antibody detecting PAK2 in ELISA, IHC (p), IF (cc), IF (p) 和 IHC (fro). Suitable for 小鼠.
产品编号 ABIN744518
发货至: 中国

Quick Overview for PAK2 抗体 (pSer20) (ABIN744518)

抗原

See all PAK2 抗体
PAK2 (P21-Activated Kinase 2 (PAK2))

适用

  • 95
  • 46
  • 45
  • 3
  • 1
  • 1
小鼠

宿主

  • 91
  • 4

克隆类型

  • 80
  • 15
多克隆

标记

  • 62
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
This PAK2 antibody is un-conjugated

应用范围

  • 62
  • 49
  • 30
  • 15
  • 6
  • 5
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 12
    • 11
    • 11
    • 8
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer20

    交叉反应

    小鼠

    预测反应

    Human,Rat,Dog,Cow,Sheep,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human PAK2 around the phosphorylation site of Ser20

    亚型

    IgG
  • 应用备注

    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    PAK2 (P21-Activated Kinase 2 (PAK2))

    别名

    PAK2

    背景

    Synonyms: PAK2 phospho S20, PAK2 phospho Ser20, p-PAK2 S20, p-PAK2 Ser20, CB422, EC 2.7.11.1, Gamma PAK, hPAK65, Kinase, p21 CDKN1A-activated kinase 2a, p21 activated kinase 2, p21 protein Cdc42/Rac-activated kinase 2, p21 protein Cdc42 Rac activated kinase 2, p21-activated kinase, 65-KD antibody p21-activated protein kinase I, p21CDKN1A activated kinase 2, p58, p65PAK, PAK 2, PAK65, PAKgamma, S6 H4 kinase, Serine threonine protein kinase PAK 2.

    Background: The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.P21-activated kinase (PAK) is actually a family of serine/threonine protein kinases, members of which are activated by small molecular weight GTPases. The three most common isoforms are PAK 1, PAK 2, and PAK 3 (also known as alpha PAK, gamma PAK, and beta PAK, respectively). These kinases contain numerous regulatory elements that trigger diverse signaling processes such as those initiated by activated GTPases, interaction with Src homology 3 (SH3) domains, and caspase mediated proteolytic cleavage. Autophosphorylation of serine 141 (serine 144 for PAK 1 and serine 139 PAK 3), catalyzed by Cdc42, is required for activation of PAK.

    基因ID

    5062

    途径

    MAPK Pathway, RTK signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
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