Recombinant Actin 抗体
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Quick Overview for Recombinant Actin 抗体 (ABIN7879874)
抗原
See all Actin (ACTA1) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- Recombinant Alpha Actin 1 Antibody / ACTA1 (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant human ACTA1 protein was used as the immunogen for the recombinant Alpha Actin 1 antibody.
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亚型
- IgG, kappa
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应用备注
- Optimal dilution of the recombinant Alpha Actin 1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the recombinant Alpha Actin 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Actin (ACTA1) (Actin, alpha 1, Skeletal Muscle (ACTA1))
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别名
- Alpha Actin 1
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背景
- All eukaryotic cells express Actin, which often constitutes as much as 50 % of total cellular protein. Actin filaments can form both stable and labile structures and are crucial components of microvilli and the contractile apparatus of muscle cells. While lower eukaryotes, such as yeast, have only one Actin gene, higher eukaryotes have several isoforms encoded by a family of genes. At least six types of Actin are present in mammalian tissues and fall into three classes. a-Actin expression is limited to various types of muscle, whereas b and g are the principle constituents of filaments in other tissues. Members of the small GTPase family regulate the organization of the Actin cytoskeleton. Rho controls the assembly of Actin stress fibers and focal adhesion, Rac regulates Actin filament accumulation at the plasma membrane and Cdc42 stimulates formation of filopodia.
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UniProt
- P68133
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途径
- Caspase Cascade in Apoptosis, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development
抗原
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