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Actin 抗体 (C-Term)

Name: Actin 抗体 (C-Term)
SKU: ABIN3043519
Availability: OutOfStock

This 兔多克隆 antibody specifically detects Actin in WB 和 IHC. It exhibits reactivity toward 人, 小鼠和大鼠. It has been mentioned in 64+ publications

Western Blotting (WB) image for anti-Actin, alpha 1, Skeletal Muscle (ACTA1) (C-Term) antibody (ABIN3043519) (Actin 抗体 (C-Term))

IHC analysis of Actin using anti-Actin antibody (ABIN3043519). (Actin 抗体 (C-Term))

IHC

IHC (p)

Western blot analysis of Actin using anti-Actin antibody (ABIN3043519). (Actin 抗体 (C-Term))

IHC

9 images

(64 references)

产品编号 ABIN3043519

发货至: 中国

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中国
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Quick Overview for Actin 抗体 (C-Term) (ABIN3043519)

抗原

See all Actin (ACTA1) 抗体

Actin (ACTA1) (Actin, alpha 1, Skeletal Muscle (ACTA1))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This Actin antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC)

抗原表位
42

9

8

6

6

5

4

1

1

1

1

1

1

1

1

1

1

1
C-Term

原理

Anti-Actin/ACTA1 Antibody

序列

HETTYNSIMK CDIDIRKDLY ANNVMSGGTT MY

特异性

No cross reactivity with other proteins.

交叉反应（详细）

No cross-reactivity with other proteins.

预测反应

identical to the related mouse,rat sequences.

产品特性

Anti-Actin/ACTA1 Antibody. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the C-terminus of human Actin, identical to the related mouse and rat sequences.

亚型

IgG
anti-Actin, alpha 1, Skeletal Muscle (ACTA1) antibody
ACTA1 适用: 人, 大鼠, 斑马鱼, 兔, Pig, 小鸡, 猴 WB, ELISA, IHC, IHC (p), IHC (fro), EM 宿主: 小鼠 Monoclonal HHF35 unconjugated

anti-Actin, alpha 1, Skeletal Muscle (ACTA1) (AA 346-375), (C-Term) antibody
ACTA1 适用: 人 WB, FACS, IHC (p), IF 宿主: 兔 Polyclonal RB35391 unconjugated

anti-Actin, alpha 1, Skeletal Muscle (ACTA1) (AA 1-129) antibody
ACTA1 适用: 人, 斑马鱼, 鱼 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Actin, alpha 1, Skeletal Muscle (ACTA1) antibody
ACTA1 适用: 人 WB, ELISA, IHC, FACS, IF 宿主: 兔 Monoclonal 25E3 unconjugated Recombinant Antibody

anti-Actin, alpha 1, Skeletal Muscle (ACTA1) (AA 3-377) antibody
ACTA1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Actin, alpha 1, Skeletal Muscle (ACTA1) (AA 346-375) antibody
ACTA1 适用: 人 WB, ELISA, IHC, FACS, IF 宿主: 兔 Polyclonal unconjugated

anti-Actin, alpha 1, Skeletal Muscle (ACTA1) antibody
ACTA1 适用: 人 WB, FACS, IHC (p) 宿主: 小鼠 Monoclonal 7C1 unconjugated

anti-Actin, alpha 1, Skeletal Muscle (ACTA1) antibody
ACTA1 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF, IP 宿主: 小鼠 Monoclonal 4A6 unconjugated

anti-Actin, alpha 1, Skeletal Muscle (ACTA1) (N-Term) antibody
ACTA1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Actin, alpha 1, Skeletal Muscle (ACTA1) (AA 7-377) antibody
ACTA1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

有效期

12 months
Cui, Wang, Yu, Li, Xie, Gao, Wang, Zhu: "Jia-Shen decoction-medicated serum inhibits angiotensin-II induced cardiac fibroblast proliferation via the TGF-β1/Smad signaling pathway." in: Molecular medicine reports, Vol. 14, Issue 2, pp. 1610-6, (2017) (PubMed).

Yan, Chen, Gong, Yin, Zhou, Chaugai, Wang: "miR-21-3p regulates cardiac hypertrophic response by targeting histone deacetylase-8." in: Cardiovascular research, Vol. 105, Issue 3, pp. 340-52, (2015) (PubMed).

Mitsuhashi, Shindo, Shigetomi, Miyamoto, Ubukata: "(+)-Epogymnolactam, a novel autophagy inducer from mycelial culture of Gymnopus sp." in: Phytochemistry, Vol. 114, pp. 163-7, (2015) (PubMed).

Wu, Sun, Wu, Li, Du, Zeng, Bi, Sun: "Activation of calcium-sensing receptor increases TRPC3/6 expression in T lymphocyte in sepsis." in: Molecular immunology, Vol. 64, Issue 1, pp. 18-25, (2015) (PubMed).

Hong, Zhang, Zhang, Yang, Wan, Yu, Wang, Feng, Li, Yew: "Expression of dopamine transporter in the different cerebral regions of methamphetamine-dependent rats." in: Human & experimental toxicology, Vol. 34, Issue 7, pp. 707-17, (2015) (PubMed).

Xie, Zhang, Chen, Pan, Wu, Ge, Yang: "Effects of ghrelin on postresuscitation brain injury in a rat model of cardiac arrest." in: Shock (Augusta, Ga.), Vol. 43, Issue 5, pp. 490-6, (2015) (PubMed).

Dai, Yin, Zhao, Guo, Li, Ma, Lu: "III-10, a newly synthesized flavonoid, induces cell apoptosis with the involvement of reactive oxygen species-mitochondria pathway in human hepatocellular carcinoma cells." in: European journal of pharmacology, Vol. 764, pp. 353-62, (2015) (PubMed).

Cheng, Ji, Liu, Mei, Wang, Feng, Ding: "Erratum: Expression changes of ionic channels in early phase of cultured rat atrial myocytes induced by rapid pacing." in: Journal of cardiothoracic surgery, Vol. 10, pp. 10, (2015) (PubMed).

Liu, Wang, Wang, Wang: "Anticancer effects of chemokine receptor 4(CXCR4) gene silenced by CXCR4-siRNA in nude mice model of ovarian cancer." in: Cell biochemistry and biophysics, Vol. 70, Issue 3, pp. 1893-900, (2014) (PubMed).

Chen, Yang, Pang, Peng, Dong, Liu, Ouyang, Ren: "Expression, purification and antibody preparation using different constructs of PCV2 capsid protein." in: International journal of biological macromolecules, Vol. 67, pp. 289-94, (2014) (PubMed).

Gong, Liu, Ding, Liu, Li, Zheng, Jia, Zhou, Zou, Li, Huang, Fan: "Physiological pulsatile flow culture conditions to generate functional endothelium on a sulfated silk fibroin nanofibrous scaffold." in: Biomaterials, Vol. 35, Issue 17, pp. 4782-91, (2014) (PubMed).

Tao, Fu, Wang, Yao, Zhou, Dai, Li, Lu, Wang: "LL-202, a newly synthesized flavonoid, inhibits tumor growth via inducing G(2)/M phase arrest and cell apoptosis in MCF-7 human breast cancer cells in vitro and in vivo." in: Toxicology letters, Vol. 228, Issue 1, pp. 1-12, (2014) (PubMed).

Li, Chen, Ouyang, Chen, Wu, Kuang, Zheng: "Increased autophagy sustains the survival and pro-tumourigenic effects of neutrophils in human hepatocellular carcinoma." in: Journal of hepatology, Vol. 62, Issue 1, pp. 131-9, (2014) (PubMed).

Zhou, Wang, Tokunaga, Huang, Sun, Yang: "The HIV-1 accessory protein Vpr induces the degradation of the anti-HIV-1 agent APOBEC3G through a VprBP-mediated proteasomal pathway." in: Virus research, Vol. 195, pp. 25-34, (2014) (PubMed).

Tang, Liu, Yang, Xie, Ye, Wu, Liu, Chen, Zhang, Xie: "miR-185 suppresses tumor proliferation by directly targeting E2F6 and DNMT1 and indirectly upregulating BRCA1 in triple-negative breast cancer." in: Molecular cancer therapeutics, Vol. 13, Issue 12, pp. 3185-97, (2014) (PubMed).

Cheng, Zhao, Wang, Lu, Wang, Wang, Yao: "The effect of 5'-adenylic acid on hepatic proteome of mice radiated by 60Co γ-ray." in: International journal of molecular sciences, Vol. 15, Issue 1, pp. 186-202, (2014) (PubMed).

Li, Chen, Li, Zhang, Tang: "Cytotoxicity of polyaniline nanomaterial on rat celiac macrophages in vitro." in: PLoS ONE, Vol. 9, Issue 9, pp. e107361, (2014) (PubMed).

Li, Shang: "Inhaled corticosteroids inhibit substance P receptor expression in asthmatic rat airway smooth muscle cells." in: BMC pulmonary medicine, Vol. 12, pp. 79, (2013) (PubMed).

Yu, Dai, Chen, Zang, Deng, Liu, Ying: "Hypolipidemic and antioxidant activities of polysaccharides from Rosae Laevigatae Fructus in rats." in: Carbohydrate polymers, Vol. 94, Issue 1, pp. 56-62, (2013) (PubMed).

Leng, Wang, Pang, Zhan, Zhang, Wang, Gao, Qian: "Evidence of a role for both anti-Hsp70 antibody and endothelial surface membrane Hsp70 in atherosclerosis." in: Cell stress & chaperones, Vol. 18, Issue 4, pp. 483-93, (2013) (PubMed).

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抗原

Actin (ACTA1) (Actin, alpha 1, Skeletal Muscle (ACTA1))

别名

ACTA1

背景

Background: Actin, a highly conserved protein, is a major component of both the cytoskeletal and contractile structures in the cell types. It varies in amount, being related to the type of differentiation and to the functional state of cells and tissues. The actins exhibit over 90 % sequence homology, but each isoform has a unique NH2-terminal sequence. The isoforms are comprised of three alpha-actin, one beta-actin, two gamma-actin. Because the amino acid sequence of the C-terminal is the same for almost all actins, this antibody has been raised using a synthetic peptide corresponding to the C-terminal 11 residues.
Gene Full Name: actin alpha 1, skeletal muscle

分子量

42 kDa

基因ID

58

UniProt

P68133

途径

Caspase Cascade in Apoptosis, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development