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Tyrosinase-Related Protein 1 抗体 (full length)

The 小鼠 单克隆 anti-Tyrosinase-Related Protein 1 antibody is suitable to detect Tyrosinase-Related Protein 1 in samples from 人. It has been validated for IHC (p).
产品编号 ABIN7879272
发货至: 中国
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Quick Overview for Tyrosinase-Related Protein 1 抗体 (full length) (ABIN7879272)

抗原

See all Tyrosinase-Related Protein 1 (TYRP1) 抗体
Tyrosinase-Related Protein 1 (TYRP1)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Tyrosinase-Related Protein 1 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

TA99-TYRP1-807
  • 抗原表位

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    full length

    原理

    TRP1 Antibody Cocktail / Tyrosinase-Related Protein-1 / TYRP1 (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    SK-MEL-23 cells (clone TA99) and recombinant full-length human TYRP1 protein (clone TYRP1/807) were used as the immunogen for the TRP1 antibody cocktail.

    亚型

    IgG2a, kappa
  • 应用备注

    Optimal dilution of the TRP1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the TRP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    Tyrosinase-Related Protein 1 (TYRP1)

    别名

    TRP1

    背景

    It reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.

    UniProt

    P17643
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