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CD1c 抗体 (full length)

This 小鼠 单克隆 antibody specifically detects CD1c in ELISA. It exhibits reactivity toward 人.
产品编号 ABIN7879115
发货至: 中国
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中国
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Room 801-803
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Quick Overview for CD1c 抗体 (full length) (ABIN7879115)

抗原

See all CD1c (CD1C) 抗体
CD1c (CD1C) (T-cell surface glycoprotein CD1c (CD1C))

适用

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宿主

  • 29
  • 26
  • 1
小鼠

克隆类型

  • 30
  • 26
单克隆

标记

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This CD1c antibody is un-conjugated

应用范围

  • 27
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ELISA

质量等级

Carrier-free

克隆位点

CD1C-1603
  • 抗原表位

    • 8
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    • 1
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    full length

    原理

    CD1c Antibody (azide and preservative free)

    纯化方法

    Protein G affinity chromatography

    免疫原

    A recombinant full-length human CD1c protein was used as the immunogen for this CD1c antibody.

    亚型

    IgG1, kappa
  • 应用备注

    Optimal dilution of the CD1c antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the CD1c antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    CD1c (CD1C) (T-cell surface glycoprotein CD1c (CD1C))

    别名

    CD1c

    背景

    The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. CD1 antigens are associated with -2-Microglobulin and expressed on cortical thymocytes, Langerhans cells, a B cell subset and some dendritic cells. Specifically, CD1A is a marker for Langerhans cell histiocytosis (LCH) and is found on interdigitating cells. Adaptor-protein complexes and CD1-associated chaperones control CD1 trafficking, and the development and activation of CD1-restricted T cells. Constitutive endocytosis of CD1B molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. CD1B is also expressed in interdigitating cells. The human CD1 genes are all closely linked in a cluster mapping at chromosome 1q23.1

    UniProt

    P29017
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