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CD1c 抗体

CD1C 适用: 人 ELISA, Coat 宿主: 小鼠 Monoclonal CD1C-1603 unconjugated
产品编号 ABIN6941008
发货至: 中国
  • 抗原 See all CD1c (CD1C) 抗体
    CD1c (CD1C) (T-cell surface glycoprotein CD1c (CD1C))
    适用
    • 46
    • 3
    • 3
    • 1
    • 1
    宿主
    • 26
    • 19
    • 1
    小鼠
    克隆类型
    • 28
    • 18
    单克隆
    标记
    • 23
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    This CD1c antibody is un-conjugated
    应用范围
    • 27
    • 27
    • 13
    • 8
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
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    ELISA, Coating (Coat)
    纯化方法
    Purified by Protein A/G
    免疫原
    Recombinant full-length human CD1c protein
    克隆位点
    CD1C-1603
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CD1C Primary Antibody
  • 应用备注

    Positive Control: Expressed on cortical thymocytes, on certain T-cell leukemias and in various other tissues.

    Known Application: ELISA (For coating, order Ab without BSA), Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    CD1c (CD1C) (T-cell surface glycoprotein CD1c (CD1C))
    别名
    CD1C (CD1C 产品)
    别名
    BDCA1 antibody, CD1 antibody, CD1A antibody, R7 antibody, CD1c molecule antibody, CD1C antibody
    背景
    The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. CD1 antigens are associated with -2-Microglobulin and expressed on cortical thymocytes, Langerhans cells, a B cell subset and some dendritic cells. Specifically, CD1A is a marker for Langerhans cell histiocytosis (LCH) and is found on interdigitating cells. Adaptor-protein complexes and CD1-associated chaperones control CD1 trafficking, and the development and activation of CD1-restricted T cells. Constitutive endocytosis of CD1B molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. CD1B is also expressed in interdigitating cells. The human CD1 genes are all closely linked in a cluster mapping at chromosome 1q23.1
    分子量
    43kDa
    基因ID
    911
    UniProt
    P29017
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