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Recombinant Melanoma gp100 抗体 (full length)

The 小鼠 单克隆 anti-Melanoma gp100 antibody is suitable to detect Melanoma gp100 in samples from 人. It has been validated for IHC (p).
产品编号 ABIN7878840
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for Recombinant Melanoma gp100 抗体 (full length) (ABIN7878840)

抗原

See all Melanoma gp100 (PMEL) 抗体
Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))

抗体类型

Recombinant Antibody

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Melanoma gp100 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RPMEL17-6821
  • 抗原表位

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    full length

    原理

    Recombinant PMEL17 Antibody / Melanoma gp100

    纯化方法

    Protein A/G affinity

    免疫原

    Recombinant full-length human protein was used as the immunogen for the recombinant PMEL17 antibody.

    亚型

    IgG1, kappa
  • 应用备注

    Optimal dilution of the recombinant PMEL17 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the recombinant PMEL17 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))

    别名

    PMEL17

    背景

    The gp100 Molecule is a 100 kDa glycosylated protein that is cleaved into a small (26 kDa) carboxy-terminal fragment and a larger amino- terminal section (60 64 kDa), which is subsequently cleaved to generate 26 kDa and 34 38 kDa fragments. By immunohistochemistry, it specifically recognizes a protein in melanocytes and melanomas. This MAb reacts with junctional and blue nevus cells and variably with fetal and neonatal melanocytes. Intradermal nevi, normal adult melanocytes, and non-melanocytic cells are negative. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin. Metastatic amelanotic melanoma can often be confused with a variety of poorly differentiated carcinomas, large cell lymphomas, and sarcomas using H E stains alone. It is also difficult to differentiate melanoma from spindle cell carcinomas and various types of mesenchymal neoplasms. This MAb stains fetal and neonatal melanocytes, junctional and blue nevus cells, and malignant melanoma. This MAb also stains Angiomyolipoma (PEComa).

    UniProt

    P40967
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