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Recombinant Melanoma gp100 抗体 (full length)

This 小鼠 单克隆 antibody specifically detects Melanoma gp100 in IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7878839
发货至: 中国
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北京 101111
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Quick Overview for Recombinant Melanoma gp100 抗体 (full length) (ABIN7878839)

抗原

See all Melanoma gp100 (PMEL) 抗体
Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))

抗体类型

Recombinant Antibody

适用

  • 145
  • 15
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  • 7
  • 3
  • 1
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宿主

  • 74
  • 68
  • 4
  • 1
小鼠

克隆类型

  • 93
  • 50
  • 3
单克隆

标记

  • 74
  • 10
  • 5
  • 5
  • 5
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  • 5
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This Melanoma gp100 antibody is un-conjugated

应用范围

  • 83
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  • 20
  • 17
  • 7
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  • 1
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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

RPMEL17-6821
  • 抗原表位

    • 20
    • 7
    • 7
    • 4
    • 4
    • 4
    • 4
    • 3
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    • 2
    • 1
    • 1
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    • 1
    full length

    原理

    Recombinant PMEL17 Antibody / Melanoma gp100 (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    Recombinant full-length human protein was used as the immunogen for the recombinant PMEL17 antibody.

    亚型

    IgG1, kappa
  • 应用备注

    Optimal dilution of the recombinant PMEL17 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the recombinant PMEL17 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))

    别名

    PMEL17

    背景

    The gp100 Molecule is a 100 kDa glycosylated protein that is cleaved into a small (26 kDa) carboxy-terminal fragment and a larger amino- terminal section (60 64 kDa), which is subsequently cleaved to generate 26 kDa and 34 38 kDa fragments. By immunohistochemistry, it specifically recognizes a protein in melanocytes and melanomas. This MAb reacts with junctional and blue nevus cells and variably with fetal and neonatal melanocytes. Intradermal nevi, normal adult melanocytes, and non-melanocytic cells are negative. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin. Metastatic amelanotic melanoma can often be confused with a variety of poorly differentiated carcinomas, large cell lymphomas, and sarcomas using H E stains alone. It is also difficult to differentiate melanoma from spindle cell carcinomas and various types of mesenchymal neoplasms. This MAb stains fetal and neonatal melanocytes, junctional and blue nevus cells, and malignant melanoma. This MAb also stains Angiomyolipoma (PEComa).

    UniProt

    P40967
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