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Recombinant MSH2 抗体 (full length)

This 小鼠 单克隆 antibody specifically detects MSH2 in WB 和 IHC (p). It exhibits reactivity toward 人, 犬 和 Cat.
产品编号 ABIN7878623
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant MSH2 抗体 (full length) (ABIN7878623)

抗原

See all MSH2 抗体
MSH2 (Mismatch Repair Protein 2 (MSH2))

抗体类型

Recombinant Antibody

适用

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人, 犬, Cat

宿主

  • 93
  • 48
小鼠

克隆类型

  • 71
  • 70
  • 1
单克隆

标记

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This MSH2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

RMSH2-6548
  • 抗原表位

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    full length

    原理

    Recombinant MSH2 Antibody (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    Recombinant full-length human MSH2 protein was used as the immunogen for the recombinant MSH2 antibody.

    亚型

    IgG2a, kappa
  • 应用备注

    Optimal dilution of the recombinant MSH2 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the recombinant MSH2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    MSH2 (Mismatch Repair Protein 2 (MSH2))

    别名

    MSH2

    背景

    Mutations in DNA mismatch repair genes are associated with hereditary nonpolyposis colorectal cancer (HNPCC). Initially, inherited mutations in the MSH2 and MLH1 homologs of the bacterial DNA mismatch repair genes MutS and MutL were found at high frequency in HNPCC and were shown to be associated with microsatellite instability. The demonstration that 10 to 45 % of pancreatic, gastric, breast, ovarian and small cell lung cancers also display microsatellite instability has been interpreted to suggest that DNA mismatch repair is not restricted to HNPCC tumors but is a common feature in tumor initiation or progression.

    途径

    DNA Damage Repair, Production of Molecular Mediator of Immune Response
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