Recombinant MSH2 抗体 (full length)
Our Local Distributor
北京 101111
Quick Overview for Recombinant MSH2 抗体 (full length) (ABIN7878619)
抗原
See all MSH2 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
-
-
抗原表位
- full length
-
原理
- MSH2 Antibody (azide and preservative free)
-
纯化方法
- Protein A/G affinity
-
免疫原
- Recombinant full-length human MSH2 protein was used as the immunogen for the MSH2 antibody.
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal dilution of the MSH2 antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
-
储存液
- Azide free
-
储存条件
- -20 °C
-
储存方法
- Aliquot the MSH2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
-
-
- MSH2 (Mismatch Repair Protein 2 (MSH2))
-
别名
- MSH2
-
背景
- Mutations in DNA mismatch repair genes are associated with hereditary nonpolyposis colorectal cancer (HNPCC). Initially, inherited mutations in the MSH2 and MLH1 homologs of the bacterial DNA mismatch repair genes MutS and MutL were found at high frequency in HNPCC and were shown to be associated with microsatellite instability. The demonstration that 10 to 45 % of pancreatic, gastric, breast, ovarian and small cell lung cancers also display microsatellite instability has been interpreted to suggest that DNA mismatch repair is not restricted to HNPCC tumors but is a common feature in tumor initiation or progression.
-
途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
抗原
-