CD44 抗体 (full length)
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Quick Overview for CD44 抗体 (full length) (ABIN7877891)
抗原
See all CD44 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- full length
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原理
- CD44 Antibody / H-CAM (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant full-length human CD44 protein was used as the immunogen for the CD44 antibody.
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亚型
- IgG2a, kappa
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应用备注
- Optimal dilution of the CD44 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the CD44 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- CD44
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别名
- CD44
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背景
- This antibody recognizes an epitope encoded by exon v3 on the variant portion of human CD44. The CD44 Molecule belongs to a family of cellular adhesion molecules found on a wide range of normal and malignant cells in epithelial, mesothelial and hemopoiesis tissues. CD44 is a single gene with 20 exons, of which 10 are normally expressed to encode the basic CD44 (H-CAM) molecule. The additional 10 exons (v1 to v10) are only expressed by alternative splicing of the nuclear RNA.The expression of specific cell adhesion molecule CD44 splice variants has been reported to be associated with metastasis in certain human malignancies.
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UniProt
- P16070
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途径
- Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
抗原
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