Calpastatin 抗体 (full length)
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北京 101111
Quick Overview for Calpastatin 抗体 (full length) (ABIN7877761)
抗原
See all Calpastatin (CAST) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- full length
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原理
- Calpastatin Antibody (azide and preservative free)
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纯化方法
- Protein G affinity chromatography
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免疫原
- A recombinant full-length human CAST protein was used as the immunogen for this Calpastatin antibody.
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亚型
- IgG1, kappa
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anti-Calpastatin (CAST) antibody
CAST 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal CAST-1550 unconjugated
anti-Calpastatin (CAST) (AA 582-669) antibodyCAST 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2C5 unconjugated
anti-Calpastatin (CAST) (AA 1-667) antibodyCAST 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Calpastatin (CAST) antibodyKD Validated CAST 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 24GB6455 unconjugated
anti-Calpastatin (CAST) (AA 1-350) antibodyCAST 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Calpastatin (CAST) (AA 275-310), (Middle Region) antibodyCAST 适用: 人 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Calpastatin (CAST) (AA 431-530) antibodyCAST 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Calpastatin (CAST) (AA 1-667) antibodyCAST 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Calpastatin (CAST) (AA 1-686) antibodyCAST 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Calpastatin (CAST) antibody (FITC)CAST 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal FITC
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应用备注
- Optimal dilution of the Calpastatin antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the Calpastatin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Calpastatin (CAST)
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别名
- Calpastatin
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背景
- Calpastatin is an intracellular calcium-dependent protease that cleaves cytoskeletal and sub-membranous proteins. Calpains are non-lysosomal, calcium-activated intracellular cysteine proteases. Calpains mediate specific Ca2+- dependent processes including cell fusion, mitosis and meiosis. Calpains are heterodimers of a small regulatory subunit and one of three large catalytic subunits, designated Calpastatin, Calpain 2 and Calpain p94. Calpastatin regulates Calpain by inhibiting both the proteolytic activity of Calpain and its binding to membranes. Calpastatin exists in two types, tissue type and erythrocyte type, resulting from both alternative splicing and proteolytic processing. Calpastatin co-localizes with human leukocyte antigen-DR (HLA-DR) on activated microglia in the aging brain. Calpain influences the process of spermatogenesis and the events preceding fertilization, such as the acrosome reaction.
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UniProt
- P20810
抗原
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