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Recombinant AMACR 抗体 (full length)

The 兔 单克隆 anti-AMACR antibody (Clone AMACR-8350R) (ABIN7877653) specifically detects AMACR in WB 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7877653
发货至: 中国
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Quick Overview for Recombinant AMACR 抗体 (full length) (ABIN7877653)

抗原

See all AMACR 抗体
AMACR (alpha-Methylacyl-CoA Racemase (AMACR))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This AMACR antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

AMACR-8350R
  • 抗原表位

    • 41
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    full length

    原理

    AMACR / p504S Antibody

    纯化方法

    Protein A/G affinity

    免疫原

    Recombinant full-length human AMACR protein was used as the immunogen for the AMACR / p504S antibody.

    亚型

    IgG, kappa
  • 应用备注

    Optimal dilution of the AMACR / p504S antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the AMACR / p504S antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    AMACR (alpha-Methylacyl-CoA Racemase (AMACR))

    别名

    AMACR / p504S

    背景

    This antibody recognizes a protein of 42 kDa, which is identified as AMACR, also known as p504S. It is an enzyme that is involved in bile acid biosynthesis and beta-oxidation of branched-chain fatty acids. AMACR is essential in lipid metabolism. It is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands. AMACR is expressed in normal liver (hepatocytes), kidney (tubular epithelial cells) and gall bladder (epithelial cells). Expression has also been found in lung (bronchial epithelial cells) and colon (colonic surface epithelium). AMACR expression can also be found in hepatocellular carcinoma and kidney carcinoma. Past studies have also shown that AMACR is expressed in various colon carcinomas (well, moderately and poorly differentiated) and over expressed in prostate carcinoma.

    UniProt

    Q9UHK6

    途径

    Monocarboxylic Acid Catabolic Process
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