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IRF5 抗体 (AA 98-477)

The 兔 多克隆 anti-IRF5 antibody is suitable to detect IRF5 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, ELISA, IF 和 FACS.
产品编号 ABIN7877286
发货至: 中国
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Quick Overview for IRF5 抗体 (AA 98-477) (ABIN7877286)

抗原

See all IRF5 抗体
IRF5 (Interferon Regulatory Factor 5 (IRF5))

适用

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人, 小鼠, 大鼠

宿主

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  • 9
  • 1
  • 1

克隆类型

  • 55
  • 38
多克隆

标记

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This IRF5 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)
  • 抗原表位

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    AA 98-477

    原理

    Interferon regulatory factor 5 Antibody / IRF5

    纯化方法

    Antigen affinity chromatography

    免疫原

    An E.coli-derived human recombinant protein (amino acids R98-A477) was used as the immunogen for the Interferon regulatory factor 5 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the Interferon regulatory factor 5 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the Interferon regulatory factor 5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    IRF5 (Interferon Regulatory Factor 5 (IRF5))

    别名

    Interferon regulatory factor 5

    背景

    Interferon regulatory factor 5, also called IRF5 or SLEB10, is a protein that in humans is encoded by the IRF5 gene. IRF5 gene is mapped to 7q32.1. This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Multiple transcript variants encoding different isoforms have been found for this gene, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment. This gene is a transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection.

    UniProt

    Q13568

    途径

    TLR signaling, Autophagy
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