IRF5 抗体 (AA 98-477)
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Quick Overview for IRF5 抗体 (AA 98-477) (ABIN7877286)
抗原
See all IRF5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 98-477
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原理
- Interferon regulatory factor 5 Antibody / IRF5
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纯化方法
- Antigen affinity chromatography
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免疫原
- An E.coli-derived human recombinant protein (amino acids R98-A477) was used as the immunogen for the Interferon regulatory factor 5 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Interferon regulatory factor 5 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Interferon regulatory factor 5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- IRF5 (Interferon Regulatory Factor 5 (IRF5))
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别名
- Interferon regulatory factor 5
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背景
- Interferon regulatory factor 5, also called IRF5 or SLEB10, is a protein that in humans is encoded by the IRF5 gene. IRF5 gene is mapped to 7q32.1. This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Multiple transcript variants encoding different isoforms have been found for this gene, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment. This gene is a transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection.
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UniProt
- Q13568
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途径
- TLR signaling, Autophagy
抗原
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