EPH Receptor A4 抗体 (AA 875-904)
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Quick Overview for EPH Receptor A4 抗体 (AA 875-904) (ABIN7877022)
抗原
See all EPH Receptor A4 (EPHA4) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 875-904
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原理
- Ephrin type-A receptor 4 Antibody / EphA4
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纯化方法
- SAS precipitation
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免疫原
- A portion of amino acids 875-904 from the human protein was used as the immunogen for the Ephrin type-A receptor 4 antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting points. Titration of the Ephrin type-A receptor 4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Aliquot the Ephrin type-A receptor 4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- EPH Receptor A4 (EPHA4)
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别名
- Ephrin type-A receptor 4
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背景
- Ephrin type-A receptor 4, also known as Eph4A, is a member of the Eph receptor family. These receptors are involved in mediating cell-to-cell communication and are critical for various physiological processes such as tissue patterning, neuronal development, and immune response. One of the key functions of Eph4A is its role in axon guidance during neuronal development. Studies have shown that Eph4A is essential for establishing proper neuronal connections in the developing brain. Disruption of Eph4A signaling has been linked to various neurological disorders, highlighting the importance of this receptor in brain development. In addition to its role in neuronal development, Eph4A has also been implicated in cancer progression. Aberrant expression of Eph4A has been observed in various types of cancer, and targeting this receptor has shown promising results in inhibiting tumor growth and metastasis. Furthermore, Eph4A has been shown to play a role in immune response regulation. By modulating the activity of immune cells, Eph4A can influence the inflammatory response and contribute to the maintenance of immune homeostasis.
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UniProt
- P54764
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途径
- RTK signaling
抗原
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