PDK4 抗体 (AA 85-129)
Our Local Distributor
北京 101111
Quick Overview for PDK4 抗体 (AA 85-129) (ABIN7876971)
抗原
See all PDK4 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 85-129
-
原理
- Pyruvate dehydrogenase kinase 4 Antibody / PDK4
-
纯化方法
- Antigen affinity purified
-
免疫原
- An E.coli-derived human recombinant protein (amino acids V85-N129) was used as the immunogen for the Pyruvate dehydrogenase kinase 4 antibody.
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal dilution of the Pyruvate dehydrogenase kinase 4 antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- 4 °C,-20 °C
-
储存方法
- After reconstitution, the Pyruvate dehydrogenase kinase 4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))
-
别名
- Pyruvate dehydrogenase kinase 4
-
背景
- Pyruvate dehydrogenase lipoamide kinase isozyme 4, mitochondrial (PDK4) is an enzyme that in humans is encoded by the PDK4 gene. This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin.
-
UniProt
- Q16654
-
途径
- PI3K-Akt Signaling, Hedgehog Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
抗原
-