PDK3 抗体 (AA 84-406)
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Quick Overview for PDK3 抗体 (AA 84-406) (ABIN7876958)
抗原
See all PDK3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 84-406
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原理
- PDK3 Antibody / Pyruvate dehydrogenase kinase 3
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纯化方法
- Antigen affinity purified
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免疫原
- An E.coli-derived human recombinant protein (amino acids Y84-Q406) was used as the immunogen for the PDK3 antibody.
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亚型
- IgG
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anti-Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3) (AA 174-263) antibody
PDK3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B11 unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3) (AA 174-263) antibodyPDK3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3A1 unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3) antibodyPDK3 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3) antibodyPDK3 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB23090 unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3) (AA 1-30), (N-Term) antibodyPDK3 适用: 人 WB 宿主: 兔 Polyclonal RB3039 unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3) (AA 137-406) antibodyPDK3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3) (Center) antibodyPDK3 适用: 人 ICC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3) (N-Term) antibodyPDK3 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 斑马鱼, 犬, 马, 兔, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3) (AA 1-406) antibodyPDK3 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3) (AA 131-362) antibodyPDK3 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the PDK3 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the PDK3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- PDK3 (Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))
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别名
- PDK3
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背景
- Pyruvate dehydrogenase lipoamide kinase isozyme 3, mitochondrial is an enzyme that in humans is encoded by the PDK3 gene. The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle, and thus is one of the major enzymes responsible for the regulation of glucose metabolism. The enzymatic activity of PDH is regulated by a phosphorylation/dephosphorylation cycle, and phosphorylation results in inactivation of PDH. The protein encoded by this gene is one of the three pyruvate dehydrogenase kinases that inhibits the PDH complex by phosphorylation of the E1 alpha subunit. This gene is predominantly expressed in the heart and skeletal muscles. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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UniProt
- Q15120
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途径
- PI3K-Akt Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
抗原
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