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KPNB1 抗体 (AA 8-871)

The 兔 多克隆 anti-KPNB1 antibody (ABIN7876846) specifically detects KPNB1 in WB. The antibody is reactive with 斑马鱼 samples.
产品编号 ABIN7876846
发货至: 中国
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Quick Overview for KPNB1 抗体 (AA 8-871) (ABIN7876846)

抗原

See all KPNB1 抗体
KPNB1 (Karyopherin (Importin) beta 1 (KPNB1))

适用

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斑马鱼

宿主

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克隆类型

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多克隆

标记

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This KPNB1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 8-871

    原理

    Zebrafish Kpnb1 Antibody / Importin Beta

    纯化方法

    Antigen affinity chromatography

    免疫原

    An E.coli-derived zebrafish Importin Beta/Kpnb1 recombinant protein (amino acids E8-K871) was used as the immunogen for the Zebrafish Kpnb1antibody.

    亚型

    Ig Fraction
  • 应用备注

    Optimal dilution of the Zebrafish Kpnb1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the Zebrafish Kpnb1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    KPNB1 (Karyopherin (Importin) beta 1 (KPNB1))

    别名

    Kpnb1

    背景

    Importin subunit beta-1 is a protein that in humans is encoded by the KPNB1 gene. Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family. Two transcript variants encoding different isoforms have been found for this gene.

    途径

    Protein targeting to Nucleus
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