Complement Factor H 抗体 (AA 751-780)
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Quick Overview for Complement Factor H 抗体 (AA 751-780) (ABIN7876733)
抗原
See all Complement Factor H (CFH) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 751-780
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原理
- Complement factor H Antibody / CFH
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 751-780 from the human protein was used as the immunogen for the Complement factor H antibody.
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亚型
- IgG
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应用备注
- The stated application concentrations are suggested starting points. Titration of the Complement factor H antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Complement factor H antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Complement Factor H (CFH)
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别名
- Complement factor H
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背景
- This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short concensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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UniProt
- P08603
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途径
- Complement System, Cellular Response to Molecule of Bacterial Origin
抗原
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