DLL4 抗体 (AA 608-641)
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北京 101111
Quick Overview for DLL4 抗体 (AA 608-641) (ABIN7876104)
抗原
See all DLL4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 608-641
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原理
- DLL4 Antibody (C-Terminal Region)
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纯化方法
- Antigen affinity
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免疫原
- A portion of amino acids 608-641 from human DLL4 was used as the immunogen for the DLL4 antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting points. Titration of the DLL4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Aliquot the DLL4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- DLL4 (delta-Like 4 (DLL4))
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别名
- DLL4
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背景
- Delta-like protein 4 is involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis, negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation is required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types. During spinal cord neurogenesis, inhibits V2a interneuron fate. [UniProt]
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UniProt
- Q9NR61
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途径
- Notch Signaling
抗原
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