DLL4 抗体 (delta-Like 4) (Internal Region)

Details for Product anti-DLL4 Antibody No. ABIN129625, 供应商: Log in to see
抗原
  • hdelta2
  • Delta4
  • si:ch211-244p18.5
  • zgc:136596
  • delta like canonical Notch ligand 4
  • delta-like 4 (Drosophila)
  • DLL4
  • Dll4
  • dll4
抗原表位
Internal Region
18
11
10
10
5
5
5
4
4
4
3
2
2
2
2
2
1
1
1
1
1
1
1
1
适用

177
79
41
4
4
4
3
3
3
2
2
1
1
1
宿主

93
72
43
13
7
克隆类型
多克隆
标记
This DLL4 antibody is un-conjugated
10
9
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6
5
4
4
4
4
4
4
4
4
3
3
3
2
1
1
1
1
1
1
1
应用范围
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
125
92
84
48
35
13
11
5
5
4
4
3
2
2
2
2
1
1
1
选项
Supplier
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Supplier Product No.
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免疫原 This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an of Human DELTA-4.
亚型 IgG
交叉反应 小鼠, 大鼠
产品特性 Concentration Definition: by UV absorbance at 280 nm
别名 DELTA-4 (DLL4 Antibody 摘要)
背景 DELTA-4 (also called delta 4 precursor, delta ligand 4 precursor, Delta-like protein 4, DLL4, Drosophila Delta homolog 4 and notch ligand DLL4 precursor) is a homolog of the Drosophila delta protein. The delta gene family encodes Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain.  DELTA-4  plays a role in the Notch signaling pathway and activates Notch-1 and Notch-4. DELTA-4 is a membrane protein that is expressed in the vascular endothelium.
Synonyms: DELTA-4, delta 4 precursor, delta ligand 4 precursor, Delta-like protein 4, DLL4, Drosophila Delta homolog 4 and notch ligand DLL4 precursor
基因ID 54567, 9506545
UniProt Q9NR61
途径 Notch Signaling
应用备注 Anti-DELTA-4 has been tested for use in ELISA, immunohistochemistry and western blotting.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 74 kDa in size corresponding to DELTA-4 by western blotting in the appropriate cell lysate or extract. For best results use Goat Serum as blocking agent in western blotting.
限制 仅限研究用
状态 Liquid
浓度 0.88 mg/mL
缓冲液 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件 -20 °C
厂商提供的图像
Immunohistochemistry (IHC) image for anti-delta-Like 4 (DLL4) (Internal Region) antibody (ABIN129625) Affinity Purified anti-Delta-4 antibody was used at 20 µg/ml to detect Delta-4 in a v...
Immunohistochemistry (IHC) image for anti-delta-Like 4 (DLL4) (Internal Region) antibody (ABIN129625) Immunohistochemistry. antibodies-online's Affinity Purified anti-Delta-4 antibody was...
 image for anti-delta-Like 4 (DLL4) (Internal Region) antibody (ABIN129625) anti-delta-Like 4 (DLL4) (Internal Region) antibody (Image 3)
 image for anti-delta-Like 4 (DLL4) (Internal Region) antibody (ABIN129625) anti-delta-Like 4 (DLL4) (Internal Region) antibody (Image 4)
ELISA image for anti-delta-Like 4 (DLL4) (Internal Region) antibody (ABIN129625) ELISA results of purified Rabbit anti-DELTA-4 Antibody tested against BSA-conjugated ...
Western Blotting (WB) image for anti-delta-Like 4 (DLL4) (Internal Region) antibody (ABIN129625) Western Blot of Rabbit anti-DELTA-4 antibody. Lane 1: Mouse Pancreas Whole Cell Lysat...
Western Blotting (WB) image for anti-delta-Like 4 (DLL4) (Internal Region) antibody (ABIN129625) Western Blot of Rabbit anti-Delta-4 antibody. Lane 1: mouse pancreatic tissue. Load: ...
 image for anti-delta-Like 4 (DLL4) (Internal Region) antibody (ABIN129625) Affinity Purified anti-Delta-4 antibody was used at 20 µg/ml to detect Delta-4 in a v...
有引用在: Zhang, Zeng, Zhang, Jiao, Li, Jing, Ouyang, Yuan, Chai, Che, Zhang, Yang: "Suppressor of cytokine signaling 3 promotes bone marrow cells to differentiate into CD8+ T lymphocytes in lung tissue via up-regulating Notch1 expression." in: Cancer research, Vol. 69, Issue 4, pp. 1578-86, 2009 (PubMed).

Indraccolo, Minuzzo, Masiero, Pusceddu, Persano, Moserle, Reboldi, Favaro, Mecarozzi, Di Mario, Screpanti, Ponzoni, Doglioni, Amadori: "Cross-talk between tumor and endothelial cells involving the Notch3-Dll4 interaction marks escape from tumor dormancy." in: Cancer research, Vol. 69, Issue 4, pp. 1314-23, 2009 (PubMed).

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