BIRC3 抗体 (AA 59-88)
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Quick Overview for BIRC3 抗体 (AA 59-88) (ABIN7875913)
抗原
See all BIRC3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 59-88
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原理
- BIRC3 Antibody
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 59-88 from the human protein was used as the immunogen for the BIRC3 antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting points. Titration of the BIRC3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the BIRC3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))
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别名
- BIRC3
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背景
- The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. The amino acid sequence predicts three baculovirus IAP repeat domains and a ring finger domain. Transcript variants encoding the same isoform have been identified. [provided by RefSeq].
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UniProt
- Q13489
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途径
- Apoptosis, Caspase Cascade in Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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