EPH Receptor A3 抗体 (AA 59-514)
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Quick Overview for EPH Receptor A3 抗体 (AA 59-514) (ABIN7875906)
抗原
See all EPH Receptor A3 (EPHA3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 59-514
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原理
- Eph receptor A3 Antibody / EphA3
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids D59-A514) was used as the immunogen for the Eph receptor A3 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Eph receptor A3 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Eph receptor A3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- EPH Receptor A3 (EPHA3)
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别名
- Eph receptor A3
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背景
- Ephrin Receptor EphA3, is also known as human embryo kinase(HEK) or Eph-like tyrosine kinase1(ETK1). Kinases that phosphorylate proteins on tyrosine residues(protein tyrosine kinases, PTKs), such as EPHA3, form a structurally related group of molecules that exhibit functional diversity. Genetic alterations that lead to the inappropriate activation or expression of PTKs may be oncogenic. Many growth factor receptors are PTKs, e.g., the receptors for epidermal growth factor(EGFR), platelet-derived growth factor(PDGFR1,PDGFR2), colony-stimulating factor-1(CSF1R), and stem cell growth factor. The EPHA3 gene is mapped to 3p11.2. Sequence comparison with other PTKs showed a high degree of homology with members of the EPH and ELK(EPHB1) families of receptor tyrosine kinases. Within axial nerves, establishment of discrete afferent and efferent pathways depends on coordinate signaling between coextending sensory and motor projections.
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UniProt
- P29320
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途径
- RTK signaling, Regulation of Cell Size
抗原
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