Calnexin 抗体 (AA 560-592)
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北京 101111
Quick Overview for Calnexin 抗体 (AA 560-592) (ABIN7875783)
抗原
See all Calnexin (CANX) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 560-592
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原理
- Calnexin Antibody (C-Terminal Region)
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纯化方法
- Antigen affinity
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免疫原
- A portion of amino acids 560-592 from human Calnexin was used as the immunogen for the Calnexin antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting points. Titration of the Calnexin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Calnexin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Calnexin (CANX)
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别名
- Calnexin
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背景
- Calnexin is a calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor- mediated endocytosis at the synapse. [UniProt]
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UniProt
- P27824
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途径
- MAPK Pathway, Thyroid Hormone Synthesis
抗原
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