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C1S 抗体 (AA 560-589)

This 兔 多克隆 antibody specifically detects C1S in WB 和 IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7875782
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for C1S 抗体 (AA 560-589) (ABIN7875782)

抗原

See all C1S 抗体
C1S (Complement Component 1, S Subcomponent (C1S))

适用

  • 89
  • 20
  • 17
  • 2
  • 1

宿主

  • 64
  • 21
  • 2
  • 2

克隆类型

  • 55
  • 34
多克隆

标记

  • 47
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This C1S antibody is un-conjugated

应用范围

  • 61
  • 31
  • 21
  • 20
  • 13
  • 13
  • 13
  • 11
  • 11
  • 8
  • 6
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 15
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 560-589

    原理

    C1S Antibody / Complement C1s subcomponent

    免疫原

    A portion of amino acids 560-589 from the human protein was used as the immunogen for the C1S antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the C1S antibody may be required due to differences in protocols and secondary/substrate sensitivity.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide and 50 % glycerol

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store the C1S antibody at -20oC.
  • 抗原

    C1S (Complement Component 1, S Subcomponent (C1S))

    别名

    C1S

    背景

    C1S, also called Complement C1s subcomponent, is a serine protease enzyme that plays a significant role in the activation of the Complement system, which is a part of the innate immune system. C1S is a key component of the C1 complex, which is the first step in the Complement activation cascade. One of the main functions of C1S is to cleave C4 and C2 proteins, leading to the formation of the C3 convertase enzyme. This enzyme then cleaves C3 protein into two parts, C3a and C3b, which mediate various immune responses such as inflammation, opsonization, and cell lysis. Overall, the activation of the Complement system through C1S plays a critical role in enhancing the immune response and clearing pathogens from our bodies. In addition to its role in immune defense, C1S has also been implicated in other physiological processes such as inflammation, tissue repair, and development. Dysregulation of C1S activity has been linked to various diseases, including autoimmune disorders, inflammatory conditions, and infectious diseases.

    UniProt

    P09871

    途径

    Complement System
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