C1S 抗体 (AA 560-589)
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北京 101111
Quick Overview for C1S 抗体 (AA 560-589) (ABIN7875782)
抗原
See all C1S 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 560-589
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原理
- C1S Antibody / Complement C1s subcomponent
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免疫原
- A portion of amino acids 560-589 from the human protein was used as the immunogen for the C1S antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the C1S antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide and 50 % glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store the C1S antibody at -20oC.
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- C1S (Complement Component 1, S Subcomponent (C1S))
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别名
- C1S
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背景
- C1S, also called Complement C1s subcomponent, is a serine protease enzyme that plays a significant role in the activation of the Complement system, which is a part of the innate immune system. C1S is a key component of the C1 complex, which is the first step in the Complement activation cascade. One of the main functions of C1S is to cleave C4 and C2 proteins, leading to the formation of the C3 convertase enzyme. This enzyme then cleaves C3 protein into two parts, C3a and C3b, which mediate various immune responses such as inflammation, opsonization, and cell lysis. Overall, the activation of the Complement system through C1S plays a critical role in enhancing the immune response and clearing pathogens from our bodies. In addition to its role in immune defense, C1S has also been implicated in other physiological processes such as inflammation, tissue repair, and development. Dysregulation of C1S activity has been linked to various diseases, including autoimmune disorders, inflammatory conditions, and infectious diseases.
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UniProt
- P09871
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途径
- Complement System
抗原
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