alpha Sarcomeric Actin (AA 557-692) 抗体
The 小鼠 单克隆 anti-alpha Sarcomeric Actin antibody is suitable to detect alpha Sarcomeric Actin in samples from 人. It has been validated for IHC (p) 和 WB.
产品编号 ABIN7875747
发货至:
中国
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Quick Overview for alpha Sarcomeric Actin (AA 557-692) 抗体 (ABIN7875747)
抗原
alpha Sarcomeric Actin
适用
人
宿主
小鼠
克隆类型
单克隆
标记
非结合性
应用范围
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
质量等级
Carrier-free
克隆位点
ACTN2-3293
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抗原表位
- AA 557-692
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原理
- Sarcomeric Alpha Actinin Antibody / ACTN2 (azide and preservative free)
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纯化方法
- Protein G affinity chromatography
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免疫原
- Amino acids 557-692 from the human protein were used as the immunogen for this Sarcomeric Alpha Actinin antibody.
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亚型
- IgG1, kappa
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anti-alpha Sarcomeric Actin antibody
适用: 小鼠, 大鼠 WB, IHC, EM, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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The optimal dilution of the Sarcomeric Alpha Actinin antibody for each application should be determined by the researcher.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the Sarcomeric Alpha Actinin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- alpha Sarcomeric Actin
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别名
- Sarcomeric Alpha Actinin
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背景
- Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In non-muscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene.
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UniProt
- P35609
抗原
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