JUP 抗体 (AA 556-745)
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Quick Overview for JUP 抗体 (AA 556-745) (ABIN7875724)
抗原
See all JUP 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 556-745
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原理
- JUP Antibody / Junction Plakoglobin / Gamma Catenin
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids M556-A745) was used as the immunogen for the JUP antibody.
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亚型
- IgG1
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应用备注
- Optimal dilution of the JUP antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the JUP antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- JUP (Junction Plakoglobin (JUP))
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别名
- JUP
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背景
- Junction plakoglobin (JUP), also known as gamma-catenin, is a protein that in humans is encoded by the JUP gene. It is a member of the catenin protein family and homologous to g-catenin, and it is mapped to 17q21.2. This gene encodes a major cytoplasmic protein that is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins. Meanwhile, JUP may have distinct roles in Wnt signaling and cancer via differential effects on downstream target genes.
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UniProt
- P14923
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途径
- Cell-Cell Junction Organization, Maintenance of Protein Location
抗原
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