RHOBTB2 抗体 (AA 554-604)
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Quick Overview for RHOBTB2 抗体 (AA 554-604) (ABIN7875718)
抗原
See all RHOBTB2 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 554-604
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原理
- DBC2 Antibody / RHOBTB2 (azide and preservative free)
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纯化方法
- Protein G affinity chromatography
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免疫原
- A portion of amino acids 554-604 from the human protein was used as the immunogen for the DBC2 antibody.
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亚型
- IgG2c, kappa
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anti-rho-Related BTB Domain Containing 2 (RHOBTB2) (AA 631-727) antibody
RHOBTB2 适用: 人 ELISA, WB, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-rho-Related BTB Domain Containing 2 (RHOBTB2) antibodyRHOBTB2 适用: 人, 小鼠 ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-rho-Related BTB Domain Containing 2 (RHOBTB2) (AA 510-619) antibodyRHOBTB2 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2G6 unconjugated
anti-rho-Related BTB Domain Containing 2 (RHOBTB2) (AA 1-727) antibodyRHOBTB2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-rho-Related BTB Domain Containing 2 (RHOBTB2) (AA 61-110) antibodyRHOBTB2 适用: 人, 小鼠 ELISA, IHC, WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-rho-Related BTB Domain Containing 2 (RHOBTB2) (N-Term) antibodyRHOBTB2 适用: 人, 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the DBC2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the DBC2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- RHOBTB2 (rho-Related BTB Domain Containing 2 (RHOBTB2))
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别名
- DBC2
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背景
- The Rho subfamily of Ras-related GTPases controls multiple aspects of cell function, including cytoskeletal rearrangement, nuclear signaling and cell growth. DBC-2 (deleted in breast cancer 2 gene protein), also known as RHOBTB2 (Rho-related BTB domain-containing protein 2), is a 727 amino acid member of the RhoBTB subfamily of Rho GTPases. Members of the RhoBTB subfamily are evolutionarily conserved and are characterized by a proline-rich region, a GTPase domain and two tandem BTB repeats. Expressed ubiquitously with highest levels in neural tissue, heart, brain and fetal lung, DBC-2 contains two BTB (POZ) domains through which it may bind to and regulate the function of target proteins, such as CUL-3. Additionally, DBC-2 is thought to function as a regulator of cell cycle and apoptosis events. Under normal conditions, DBC-2 is thought to exhibit tumor suppressor activity. Mutations in the gene encoding DBC-2 are associated with breast cancer, suggesting that mutated DBC-2 may play a role in carcinogenesis.
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UniProt
- Q9BYZ6
抗原
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