LEMD3 抗体 (AA 535-852)
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Quick Overview for LEMD3 抗体 (AA 535-852) (ABIN7875610)
抗原
See all LEMD3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 535-852
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原理
- MAN1 Antibody / LEMD3
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纯化方法
- Antigen affinity purified
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免疫原
- An E.coli-derived human recombinant protein (amino acids H535-H852) was used as the immunogen for the MAN1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the MAN1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the MAN1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- LEMD3 (LEM Domain Containing 3 (LEMD3))
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别名
- MAN1
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背景
- LEM domain-containing protein 3 (LEMD3), also known as MAN1, is an integral protein in the inner nuclear membrane (INM) of the nuclear envelope. It is encoded by the LEMD3 gene and was first identified after it was isolated from the serum of a patient with a collagen vascular disease. This locus encodes a LEM domain-containing protein. The encoded protein functions to antagonize transforming growth factor-beta signaling at the inner nuclear membrane. Two transcript variants encoding different isoforms have been found for this gene. Mutations in this gene have been associated with osteopoikilosis, Buschke-Ollendorff syndrome and melorheostosis.
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UniProt
- Q9Y2U8
抗原
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