LEMD3 抗体 (AA 535-852)
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北京 101111
Quick Overview for LEMD3 抗体 (AA 535-852) (ABIN8005323)
抗原
See all LEMD3 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 535-852
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原理
- Anti-LEMD3 Antibody
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交叉反应 (详细)
- No cross reactivity with other proteins.
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产品特性
- Anti-LEMD3 Antibody. Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human LEMD3 recombinant protein (Position: H535-H852).
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亚型
- IgG
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- LEMD3 (LEM Domain Containing 3 (LEMD3))
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别名
- LEMD3
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背景
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Background: LEM domain-containing protein 3 (LEMD3), also known as MAN1, is an integral protein in the inner nuclear membrane (INM) of the nuclear envelope. It is encoded by the LEMD3 gene[5] and was first identified after it was isolated from the serum of a patient with a collagen vascular disease. This locus encodes a LEM domain-containing protein. The encoded protein functions to antagonize transforming growth factor-beta signaling at the inner nuclear membrane. Two transcript variants encoding different isoforms have been found for this gene. Mutations in this gene have been associated with osteopoikilosis, Buschke-Ollendorff syndrome and melorheostosis.
Gene Full Name: LEM domain containing 3
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分子量
- 120 kDa
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基因ID
- 23592
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UniProt
- Q9Y2U8
抗原
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