TGFB3 抗体 (AA 50-250)
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北京 101111
Quick Overview for TGFB3 抗体 (AA 50-250) (ABIN7875397)
抗原
See all TGFB3 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 50-250
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原理
- TGF beta 3 Antibody / TGFB3 (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- A recombinant partial protein sequence (within amino acids 50-250) from the human protein was used as the immunogen for the TGF beta 3 antibody.
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亚型
- IgG2, kappa
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anti-Transforming Growth Factor, beta 3 (TGFB3) (AA 24-300) antibody
TGFB3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta 3 (TGFB3) (AA 24-300) antibodyTGFB3 适用: 人 WB 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Transforming Growth Factor, beta 3 (TGFB3) antibodyTGFB3 适用: 人, 大鼠, 小鼠, 猴 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta 3 (TGFB3) (AA 298-409) antibodyTGFB3 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta 3 (TGFB3) (C-Term) antibodyTGFB3 适用: 人, 大鼠, 小鼠 WB, IHC, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta 3 (TGFB3) (AA 24-300) antibodyTGFB3 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C5 unconjugated
anti-Transforming Growth Factor, beta 3 (TGFB3) (AA 274-372) antibodyTGFB3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta 3 (TGFB3) (AA 24-300) antibodyTGFB3 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta 3 (TGFB3) (AA 301-412) antibodyTGFB3 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta 3 (TGFB3) (AA 215-249) antibodyTGFB3 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB53679 unconjugated
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应用备注
- Optimal dilution of the TGF beta 3 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the TGF beta 3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- TGFB3 (Transforming Growth Factor, beta 3 (TGFB3))
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别名
- TGF beta 3
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背景
- Transforming growth factor betas (TGF-betas) were originally discovered due to their ability to promote anchorage-independent growth of rat NRK fibroblasts in the presence of TGF-beta. TGF-beta 1, TGF-beta 2 and TGF-beta 3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules. TGF-beta 3 mediates many intercellular interactions that occur during embryonic development, cell differentiation and epithelial homeostasis. TGF-beta 3 overexpresses in extramammary Paget s disease (EPD) and downregulates in Bowen s disease, indicating that its expression is a useful indicator of tumor activity. TGF-beta 3 levels strongly correlate with IGF-1 and osteocalcin levels in serum. Significant amounts of TGF-beta 3 circulation appear to be representative of TGFbeta 3 expression in bone and may in part be derived from bone. Glucocorticoids may block TGF-beta production by modulating mRNA levels and c-Jun activity.
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UniProt
- P10600
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途径
- Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
抗原
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