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- 抗原 See all TGFB3 抗体
- TGFB3 (Transforming Growth Factor, beta 3 (TGFB3))
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抗原表位
- AA 301-412
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TGFB3 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Transforming growth factor beta-3 proprotein protein (301-412AA)
- 亚型
- IgG
- Top Product
- Discover our top product TGFB3 Primary Antibody
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anti-Transforming Growth Factor, beta 3 (TGFB3) (AA 24-300) antibody
TGFB3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta 3 (TGFB3) (AA 24-300) antibodyTGFB3 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C9 unconjugated
anti-Transforming Growth Factor, beta 3 (TGFB3) antibodyTGFB3 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta 3 (TGFB3) (AA 298-409) antibodyTGFB3 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta 3 (TGFB3) (C-Term) antibodyTGFB3 适用: 人, 小鼠, 大鼠 WB, IHC, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta 3 (TGFB3) (AA 274-372) antibodyTGFB3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta 3 (TGFB3) (AA 24-300) antibodyTGFB3 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta 3 (TGFB3) (AA 215-249) antibodyTGFB3 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB53679 unconjugated
anti-Transforming Growth Factor, beta 3 (TGFB3) (AA 323-372) antibodyTGFB3 适用: 人, 小鼠, 猴, 犬, 马, 兔, 豚鼠, 斑马鱼, Hamster, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Transforming Growth Factor, beta 3 (TGFB3) (AA 150-199) antibodyTGFB3 适用: 人, Cow, 猴, 马, 兔, 绵羊, Bat WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: IHC:1:50-1:500,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- TGFB3 (Transforming Growth Factor, beta 3 (TGFB3))
- 别名
- TGFB3 (TGFB3 产品)
- 别名
- TGFB3 antibody, ARVD antibody, TGF-beta3 antibody, Tgfb-3 antibody, TGF-B3 antibody, TGFbeta3 antibody, wu:fc78g09 antibody, zgc:92058 antibody, transforming growth factor beta 3 antibody, transforming growth factor, beta 3 antibody, TGFB3 antibody, Tgfb3 antibody, tgfb3 antibody
- 背景
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Background: Transforming growth factor beta-3 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-3 (TGF-beta-3) chains, which constitute the regulatory and active subunit of TGF-beta-3, respectively.Latency-associated peptide: Required to maintain the Transforming growth factor beta-3 (TGF-beta-3) chain in a latent state during storage in extracellular matrix (By similarity). Associates non-covalently with TGF-beta-3 and regulates its activation via interaction with \\\'milieu molecules\\\', such as LTBP1 and LRRC32/GARP, that control activation of TGF-beta-3 (By similarity). Interaction with integrins results in distortion of the Latency-associated peptide chain and subsequent release of the active TGF-beta-3.Transforming growth factor beta-3: Multifunctional protein that regulates embryogenesis and cell differentiation and is required in various processes such as secondary palate development (By similarity). Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transforming growth factor beta-3 (TGF-beta-3) chains remain non-covalently linked rendering TGF-beta-3 inactive during storage in extracellular matrix (By similarity). At the same time, LAP chain interacts with \\\'milieu molecules\\\', such as LTBP1 and LRRC32/GARP that control activation of TGF-beta-3 and maintain it in a latent state during storage in extracellular milieus (By similarity). TGF-beta-3 is released from LAP by integrins: integrin-binding results in distortion of the LAP chain and subsequent release of the active TGF-beta-3 (By similarity). Once activated following release of LAP, TGF-beta-3 acts by binding to TGF-beta receptors (TGFBR1 and TGFBR2), which transduce signal (By similarity).
Aliases: ARVD antibody, ARVD1 antibody, FLJ16571 antibody, LDS5 antibody, MGC105479 antibody, MGC118722 antibody, prepro-transforming growth factor beta-3 antibody, RNHF antibody, TGF beta 3 antibody, TGF beta3 antibody, TGF-beta-3 antibody, TGFB 3 antibody, Tgfb3 antibody, TGFB3_HUMAN antibody, transforming growth factor beta 3 antibody, Transforming growth factor beta-3 antibody
- UniProt
- P10600
- 途径
- Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
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