SOX18 抗体 (AA 50-250)
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Quick Overview for SOX18 抗体 (AA 50-250) (ABIN7875393)
抗原
See all SOX18 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 50-250
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原理
- SOX18 Antibody (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- A recombinant human SOX18 protein fragment (within amino acids 50-250) was used as the immunogen for the SOX18 antibody.
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亚型
- IgG2, kappa
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应用备注
- Optimal dilution of the SOX18 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the SOX18 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- SOX18 (SRY (Sex Determining Region Y)-Box 18 (SOX18))
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别名
- SOX18
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背景
- Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNAbinding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal. Sox-18 is a 384 amino acid nuclear protein that contains one HMG box DNA-binding domain and belongs to the Sox family of transcriptional regulators.
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UniProt
- P35713
抗原
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