电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

SOX18 抗体 (Middle Region)

SOX18 适用: 人, 小鼠, 大鼠, Cow, 豚鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2777725
发货至: 中国
  • 抗原 See all SOX18 抗体
    SOX18 (SRY (Sex Determining Region Y)-Box 18 (SOX18))
    抗原表位
    • 8
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 39
    • 20
    • 15
    • 3
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 豚鼠
    宿主
    • 39
    • 3
    克隆类型
    • 32
    • 10
    多克隆
    标记
    • 18
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This SOX18 antibody is un-conjugated
    应用范围
    • 27
    • 17
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    序列
    RTAPPAAPLA GLYYGTLGTP GPYPGPLSPP PEAPPLESAE PLGPAADLWA
    预测反应
    Cow: 86%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against SOX18. It was validated on Western Blot and immunohistochemistry.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human SOX18
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 384 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Park, Lee, Park, Choi, Lee, Song, Hwang, Hong, Nakaoka, Makinen, Kim, Alitalo, Hong, Koh: "Lymphatic regulator PROX1 determines Schlemm's canal integrity and identity." in: The Journal of clinical investigation, Vol. 124, Issue 9, pp. 3960-74, (2014) (PubMed).

    Deng, Atri, Eichmann, Simons: "Endothelial ERK signaling controls lymphatic fate specification." in: The Journal of clinical investigation, Vol. 123, Issue 3, pp. 1202-15, (2013) (PubMed).

    Duong, Proulx, Luciani, Leroux, Detmar, Koopman, Francois: "Genetic ablation of SOX18 function suppresses tumor lymphangiogenesis and metastasis of melanoma in mice." in: Cancer research, Vol. 72, Issue 12, pp. 3105-14, (2012) (PubMed).

  • 抗原
    SOX18 (SRY (Sex Determining Region Y)-Box 18 (SOX18))
    别名
    SOX18 (SOX18 产品)
    别名
    HLTS antibody, AI385749 antibody, Ra antibody, Ragl antibody, sox18 antibody, xSox18alpha antibody, xSox18beta antibody, xsox18 antibody, SRY-box 18 antibody, SRY (sex determining region Y)-box 18 antibody, SRY box 18 antibody, SRY-box 18 S homeolog antibody, SRY-box 18 L homeolog antibody, SRY box 1 antibody, SOX18 antibody, Sox18 antibody, sox18.S antibody, sox18.L antibody, Sox1 antibody
    背景
    SOX18 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. This protein plays a role in hair, blood vessel, and lymphatic vessel development. Mutations in this gene have been associated with recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia.
    Alias Symbols: HLTS
    Protein Interaction Partner: GKAP1, MECP2, MEF2C, HMGB1,
    Protein Size: 384
    分子量
    41 kDa
    基因ID
    54345
    NCBI登录号
    NM_018419, NP_060889
    UniProt
    P35713
You are here:
客服