SOX18 抗体 (AA 50-250)
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Quick Overview for SOX18 抗体 (AA 50-250) (ABIN7863909)
抗原
See all SOX18 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 50-250
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原理
- SOX18 Antibody
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特异性
- Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNAbinding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal. Sox-18 is a 384 amino acid nuclear protein that contains one HMG box DNA-binding domain and belongs to the Sox family of transcriptional regulators.
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纯化方法
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant human SOX18 protein fragment (around aa 50-250) (exact sequence is proprietary)
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亚型
- IgG2, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- SOX18 (SRY (Sex Determining Region Y)-Box 18 (SOX18))
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别名
- SOX18
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背景
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HLTS, SOX 18, SRY (sex determining region Y) box 18, SRY box 18, Transcription factor SOX-18
Human heart|kidney|skin or endometrium.
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分子量
- 45kDa
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基因ID
- 54345, 8619
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UniProt
- P35713
抗原
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