MR1 抗体 (AA 50-250)
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北京 101111
Quick Overview for MR1 抗体 (AA 50-250) (ABIN7875386)
抗原
See all MR1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 50-250
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原理
- MR1 Antibody / MHC class I related protein 1
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纯化方法
- Protein A/G affinity
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免疫原
- A recombinant partial protein sequence (within amino acids 50-250) from the human protein was used as the immunogen for the MR1 antibody.
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亚型
- IgG2, kappa
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anti-Major Histocompatibility Complex, Class I-Related (MR1) (AA 201-300) antibody
MR1 适用: 人 ELISA, WB, IF 宿主: 小鼠 Monoclonal 5B5 unconjugated
anti-Major Histocompatibility Complex, Class I-Related (MR1) (AA 312-341), (C-Term) antibodyMR1 适用: 人 WB 宿主: 兔 Polyclonal RB37199 unconjugated
anti-Major Histocompatibility Complex, Class I-Related (MR1) (AA 150-253) antibodyMR1 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class I-Related (MR1) (AA 20-260) antibodyMR1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class I-Related (MR1) (AA 150-253) antibodyMR1 适用: 人, 小鼠 ELISA, WB, IHC, IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class I-Related (MR1) (AA 20-260) antibodyMR1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class I-Related (MR1) (AA 201-300) antibodyMR1 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal dilution of the MR1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the MR1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- MR1 (Major Histocompatibility Complex, Class I-Related (MR1))
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别名
- MR1
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背景
- MR1 (major histocompatibility complex, class I-related), also known as HLALS, is a 341 amino acid single-pass membrane protein that localizes to the endoplasmic reticulum, as well as to the extracellular side of the cell membrane, and contains one Ig-like C1-type domain. Expressed ubiquitously, MR1 exists as a heterodimer with b-2-Microglobulin and plays an important role in antigen presentation, specifically in the development and expansion of mucosalassociated invariant T cells (MAITs). MAITs are located in the gut and are involved in monitoring flora levels, as well as in conveying distress signals to other areas of the body, indicating a role for MR1 in proper digestion and immune system function. MR1 exists as four alternatively spliced isoforms and is encoded by a gene which maps to human chromosome 1.
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UniProt
- Q95460
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
抗原
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