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Recombinant COX2 抗体 (AA 442-572)

The 兔 单克隆 anti-COX2 antibody is suitable to detect COX2 in samples from 人. It has been validated for IHC (p).
产品编号 ABIN7875033
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for Recombinant COX2 抗体 (AA 442-572) (ABIN7875033)

抗原

See all COX2 抗体
COX2 (Cytochrome C Oxidase Subunit II (COX2))

抗体类型

Recombinant Antibody

适用

  • 106
  • 37
  • 13
  • 1

宿主

  • 103
  • 10
  • 2

克隆类型

  • 61
  • 54
单克隆

标记

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This COX2 antibody is un-conjugated

应用范围

  • 81
  • 54
  • 32
  • 26
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  • 19
  • 15
  • 11
  • 4
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

COX2-3232R
  • 抗原表位

    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 442-572

    原理

    Recombinant COX2 Antibody / PTGS2

    纯化方法

    Protein A affinity chromatography

    免疫原

    A recombinant human partial protein (amino acids 442-572) was used as the immunogen for the COX2 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the recombinant COX2 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store the recombinant COX2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    COX2 (Cytochrome C Oxidase Subunit II (COX2))

    别名

    COX2

    背景

    Prostaglandins are a diverse group of autocrine and paracrine hormones that mediate many cellular and physiologic processes. Prostaglandin H2 (PGH2) is an intermediate molecule in formation of the prostaglandins. Cyclooxygenase-1 (Cox-1) and cyclooxygenase-2 (Cox-2) are prostaglandin synthases that catalyze the formation of PGH2 from arachidonic acid (AA). Cox-1 and Cox-2 are isozymes of prostaglandin-endoperoxidase synthase (PTGS). Cox-1 is constitutively expressed in most tissues and is thought to serve in general housekeeping functions. Cox-2 is efficiently induced in migratory cells responding to pro-inflammatory stimuli and is considered to be an important mediator of inflammation. Both enzymes are targets for the nonsteroidal therapeutic anti-inflammatory drugs, NSAIDs. COX2 expression is significantly increased in 85-90 % of human colorectal adenocarcinomas whereas levels of COX-1 are not changed.

    UniProt

    P35354

    途径

    Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
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