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S100A8 抗体 (AA 400-600)

This 小鼠 单克隆 antibody specifically detects S100A8 in IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7874777
发货至: 中国
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Quick Overview for S100A8 抗体 (AA 400-600) (ABIN7874777)

抗原

See all S100A8 抗体
S100A8 (S100 Calcium Binding Protein A8 (S100A8))

适用

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宿主

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小鼠

克隆类型

  • 121
  • 49
单克隆

标记

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This S100A8 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

ABCC11-2438
  • 抗原表位

    • 24
    • 21
    • 19
    • 16
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
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    AA 400-600

    原理

    MRP8 Antibody / Multidrug resistance-associated protein 8 / ABCC11 (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    A recombinant fragment (within amino acids 400-600) of human ABCC11/MRP8 protein was used as the immunogen for the MRP8 antibody.

    亚型

    IgG2b, kappa
  • 应用备注

    Optimal dilution of the MRP8 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the MRP8 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    S100A8 (S100 Calcium Binding Protein A8 (S100A8))

    别名

    MRP8

    背景

    ATP-binding cassette (ABC) transporters belong to an evolutionarily conserved family of proteins that catalyze the transport of molecules across extra- and intracellular membranes through the energy of ATP hydrolysis. ABC genes comprise seven subfamilies, designated ABC1, MDR/TAP, MRP, ALD, OABP, GCN20 and White. The complete human ABCC subfamily has 12 identified members (ABCC1-12), nine from the multidrug resistance-like subgroup, two from the sulfonylurea receptor subgroup, and the CFTR gene. The human ABCC11 gene maps to chromosome 16q12.1 and encodes a 1,382 amino acid protein. The human ABCC12 gene maps to chromosome 16q12.1 and encodes a 1,359 amino acid protein. Transcripts of ABCC11 and ABCC12 genes are present in various adult human tissues, including liver, lung and kidney, and also in several fetal tissues. Their chromosomal localization, potential function and expression patterns identify them as candidates for paroxysmal kinesigenic choreoathetosis, a disorder characterized by attacks of involuntary movements and postures, chorea and dystonia. Other inherited disorders where ABC transporters are implicated include cystic fibrosis, neurological disease, retinal degeneration, cholesterol and bile transport defects, anemia and drug response.

    UniProt

    Q96J66

    途径

    Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, S100 Proteins
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