SOCS5 抗体 (AA 386-536)
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Quick Overview for SOCS5 抗体 (AA 386-536) (ABIN7874548)
抗原
See all SOCS5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 386-536
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原理
- SOCS5 Antibody / Suppressor of cytokine signaling 5
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纯化方法
- Antigen affinity purified
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免疫原
- Amino acids M386-K536 from the human protein were used as the immunogen for the SOCS5 antibody.
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亚型
- IgG
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anti-Suppressor of Cytokine Signaling 5 (SOCS5) (N-Term) antibody
SOCS5 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 5 (SOCS5) (AA 1-110) antibodySOCS5 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2D1 unconjugated
anti-Suppressor of Cytokine Signaling 5 (SOCS5) (AA 1-140) antibodySOCS5 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 5 (SOCS5) (AA 1-536) antibodySOCS5 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 5 (SOCS5) (AA 1-536) antibodySOCS5 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 5 (SOCS5) (AA 1-270) antibodySOCS5 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 5 (SOCS5) antibodySOCS5 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 5 (SOCS5) (AA 386-536) antibodySOCS5 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 5 (SOCS5) (AA 1-270) antibodySOCS5 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the SOCS5 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the SOCS5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- SOCS5 (Suppressor of Cytokine Signaling 5 (SOCS5))
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别名
- SOCS5
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背景
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SOCS5 (Suppressor of cytokine signaling 5) is a member of the SOCS family, a group of intracellular proteins that function as negative regulators of cytokine receptor signaling. SOCS5 contains an SH2 domain and a SOCS box motif, allowing it to interact with activated receptors and associated kinases to modulate JAK-STAT pathway activity. By preventing excessive cytokine signaling, SOCS5 maintains immune system balance and contributes to cellular homeostasis. A SOCS5 antibody is a valuable tool for investigating these regulatory mechanisms.
SOCS5 has been implicated in the regulation of interleukin and growth factor signaling. Its activity helps control cell proliferation, differentiation, and survival. Aberrant expression or dysfunction of SOCS5 has been associated with various pathological conditions, including chronic inflammation, autoimmune disorders, and certain cancers. Using a SOCS5 antibody enables researchers to evaluate its expression patterns, molecular interactions, and role in disease development.
In addition to its role in immune regulation, SOCS5 has been shown to influence neural development and epithelial cell signaling, highlighting its multifunctional nature. Studies have indicated that SOCS5 can act as a tumor suppressor in specific contexts, while in other cases, it may contribute to oncogenesis depending on the signaling environment. Employing a SOCS5 antibody allows for precise characterization of these complex roles across different biological systems.
NSJ Bioreagents offers a high-quality SOCS5 antibody validated for applications such as western blot, immunohistochemistry, and immunofluorescence. Selecting a SOCS5 antibody from NSJ Bioreagents ensures reliable performance for studies of cytokine signaling, immune regulation, and cancer biology. -
UniProt
- O75159
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途径
- JAK/STAT Signaling, EGFR Signaling Pathway, Positive Regulation of Immune Effector Process
抗原
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